BDBM50084216 (R)-4-Methoxyamino-1-(4-methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL151591

SMILES CONC1C[C@@H](N(C1)S(=O)(=O)c1ccc(OC)cc1)C(=O)NO

InChI Key InChIKey=OJLWCTMBGWSVFC-FFFFSGIJSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50084216   

Target72 kDa type IV collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084216((R)-4-Methoxyamino-1-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory activity against gelatinase-A (matrix metalloproteinase-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrilysin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084216((R)-4-Methoxyamino-1-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50:  3.39E+3nMAssay Description:In vitro inhibition of matrilysin (Matrix metalloproteinase-7, MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084216((R)-4-Methoxyamino-1-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of human recombinant collagenase-3 (Matrix metalloproteinase-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084216((R)-4-Methoxyamino-1-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibition activity of human recombinant stromelysin (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetInterstitial collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084216((R)-4-Methoxyamino-1-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50:  212nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloproteinase-1, MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed