BDBM50084219 (R)-4-[(Z)-Benzyloxyimino]-1-(4-butoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL440178

SMILES CCCCOc1ccc(cc1)S(=O)(=O)N1C\C(C[C@@H]1C(=O)NO)=N/OCc1ccccc1

InChI Key InChIKey=UBBBKPVDKLDZNE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084219   

TargetCollagenase 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084219((R)-4-[(Z)-Benzyloxyimino]-1-(4-butoxy-benzenesulf...)
Affinity DataIC50: 0.100nMAssay Description:In vitro inhibition of human recombinant collagenase-3 (Matrix metalloprotease-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084219((R)-4-[(Z)-Benzyloxyimino]-1-(4-butoxy-benzenesulf...)
Affinity DataIC50: 17nMAssay Description:In vitro inhibition activity of human recombinant stromelysin (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084219((R)-4-[(Z)-Benzyloxyimino]-1-(4-butoxy-benzenesulf...)
Affinity DataIC50: 127nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloprotease-1, MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084219((R)-4-[(Z)-Benzyloxyimino]-1-(4-butoxy-benzenesulf...)
Affinity DataIC50: 490nMAssay Description:In vitro inhibition of matrilysin (Matrix metalloprotease-7, MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed