BDBM50084220 (R)-1-(4-Methoxy-benzenesulfonyl)-4-methylene-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL151399

SMILES COc1ccc(cc1)S(=O)(=O)N1CC(=C)C[C@@H]1C(=O)NO

InChI Key InChIKey=CBDXJWSRGWXYPR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084220   

TargetCollagenase 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084220((R)-1-(4-Methoxy-benzenesulfonyl)-4-methylene-pyrr...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of human recombinant collagenase-3 (Matrix metalloprotease-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084220((R)-1-(4-Methoxy-benzenesulfonyl)-4-methylene-pyrr...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition activity of human recombinant stromelysin (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084220((R)-1-(4-Methoxy-benzenesulfonyl)-4-methylene-pyrr...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloprotease-1, MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084220((R)-1-(4-Methoxy-benzenesulfonyl)-4-methylene-pyrr...)
Affinity DataIC50: 1.23E+4nMAssay Description:In vitro inhibition of matrilysin (Matrix metalloprotease-7, MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed