BDBM50084222 (R)-4-[(Z)-Hydroxyimino]-1-(4-methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL150655

SMILES COc1ccc(cc1)S(=O)(=O)N1C=C(C[C@@H]1C(=O)NO)NO

InChI Key InChIKey=PNOYLKIRWUYKLC-LLVKDONJSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084222   

TargetInterstitial collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084222((R)-4-[(Z)-Hydroxyimino]-1-(4-methoxy-benzenesulfo...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloproteinase-1, MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084222((R)-4-[(Z)-Hydroxyimino]-1-(4-methoxy-benzenesulfo...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition activity of human recombinant stromelysin (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084222((R)-4-[(Z)-Hydroxyimino]-1-(4-methoxy-benzenesulfo...)
Affinity DataIC50:  0.200nMAssay Description:In vitro inhibition of human recombinant collagenase-3 (Matrix metalloproteinase-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084222((R)-4-[(Z)-Hydroxyimino]-1-(4-methoxy-benzenesulfo...)
Affinity DataIC50:  0.200nMAssay Description:In vitro inhibitory activity against gelatinase-A (matrix metalloproteinase-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed