BDBM50084290 (S)-2-(4'-bromo-2'-fluoro-biphenyl-4-sulfonylamino)-3-methyl-butyric acid::2-(4'-Bromo-2'-fluoro-biphenyl-4-sulfonylamino)-3-methyl-butyric acid::CHEMBL46818

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1F)C(O)=O

InChI Key InChIKey=UWHPJOBPMXNVII-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50084290   

Target72 kDa type IV collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084290(2-(4'-Bromo-2'-fluoro-biphenyl-4-sulfonylamino)-3-...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084290(2-(4'-Bromo-2'-fluoro-biphenyl-4-sulfonylamino)-3-...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084290(2-(4'-Bromo-2'-fluoro-biphenyl-4-sulfonylamino)-3-...)
Affinity DataIC50: 16nMAssay Description:In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084290(2-(4'-Bromo-2'-fluoro-biphenyl-4-sulfonylamino)-3-...)
Affinity DataIC50: 2.10E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084290(2-(4'-Bromo-2'-fluoro-biphenyl-4-sulfonylamino)-3-...)
Affinity DataIC50: 3.60E+3nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50084290(2-(4'-Bromo-2'-fluoro-biphenyl-4-sulfonylamino)-3-...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50084290(2-(4'-Bromo-2'-fluoro-biphenyl-4-sulfonylamino)-3-...)
Affinity DataIC50: 4.90E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed