BDBM50084333 (2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piperidin-4-yl]-amine::CHEMBL417049

SMILES CN(CCOC(c1ccccc1)c1ccccc1)C1CCN(CCCc2ccccc2)CC1

InChI Key InChIKey=SUFVPROIOBRYEK-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084333   

TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084333((2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piper...)
Affinity DataKi:  29nMAssay Description:Binding affinity at the norepinephrine transporter was measured using [125I]RTI-55 as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084333((2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piper...)
Affinity DataKi:  30nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084333((2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piper...)
Affinity DataIC50: 200nMAssay Description:Inhibition of [3H]NE reuptake by human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084333((2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piper...)
Affinity DataIC50: 330nMAssay Description:Inhibition of [3H]dopamine reuptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084333((2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piper...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity for serotonin transporter using [125I]RTI-55More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084333((2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piper...)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of [3H]5-HT reuptake in HEK293 cells expressing human serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed