BDBM50084431 CHEMBL3426698

SMILES O=C(CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1)N[C@H]1CC[C@H](CNC[C@H](O)c2ccc(O)c3[nH]c(=O)ccc23)CC1

InChI Key InChIKey=REUZFCAPUWZSMB-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084431   

TargetBeta-2 adrenergic receptor(Human)
Theravance Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084431BDBM50084431(CHEMBL3426698)
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as cAMP accumulation using [125I]cAMP by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Theravance Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084431BDBM50084431(CHEMBL3426698)
Affinity DataKi:  0.316nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressing CHO-K1 cells incubated for 60 mins or 6 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed