BDBM50084720 (2,4-Dichloro-phenyl)-[4-(2,4-dichloro-phenyl)-4-hydroxy-1-methyl-piperidin-3-yl]-methanone::CHEMBL331334

SMILES CN1CCC(O)(C(C1)C(=O)c1ccc(Cl)cc1Cl)c1ccc(Cl)cc1Cl

InChI Key InChIKey=FEIRROBBFMUCJM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084720   

TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084720((2,4-Dichloro-phenyl)-[4-(2,4-dichloro-phenyl)-4-h...)
Affinity DataKi:  3.65E+3nMAssay Description:Binding Affinity to cocaine site of dopamine transporter in caudate nuclei which was homogenized and incubated with [3H]mazindol. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084720((2,4-Dichloro-phenyl)-[4-(2,4-dichloro-phenyl)-4-h...)
Affinity DataKi:  5.85E+3nMAssay Description:Inhibition of [3H]DA Uptake at dopamine transporter in rat cortex was measured by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed