BDBM50085003 4-(3,4-Difluoro-phenyl)-2,5-dioxo-1,2,5,7-tetrahydro-4H-furo[3,4-d]pyrimidine-3-carboxylic acid {3-[4-(2-carbamoyl-phenyl)-piperazin-1-yl]-propyl}-amide::CHEMBL50081

SMILES NC(=O)c1ccccc1N1CCN(CCCNC(=O)N2C(C3=C(COC3=O)NC2=O)c2ccc(F)c(F)c2)CC1

InChI Key InChIKey=FMYNAWYOKZCTHQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085003   

TargetAlpha-1A adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085003(4-(3,4-Difluoro-phenyl)-2,5-dioxo-1,2,5,7-tetrahyd...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]- prazosin from human recombinant Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085003(4-(3,4-Difluoro-phenyl)-2,5-dioxo-1,2,5,7-tetrahyd...)
Affinity DataKi:  350nMAssay Description:Displacement of [3H]- prazosin from human recombinant Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085003(4-(3,4-Difluoro-phenyl)-2,5-dioxo-1,2,5,7-tetrahyd...)
Affinity DataKi:  690nMAssay Description:Displacement of [3H]- prazosin from human recombinant Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed