BDBM50085004 1-(3-{[4-(4-Nitro-phenyl)-2,5-dioxo-1,2,5,7-tetrahydro-4H-furo[3,4-d]pyrimidine-3-carbonyl]-amino}-propyl)-4-phenyl-piperidine-4-carboxylic acid methyl ester::CHEMBL301077

SMILES COC(=O)C1(CCN(CCCNC(=O)N2C(C3=C(COC3=O)NC2=O)c2ccc(cc2)[N+]([O-])=O)CC1)c1ccccc1

InChI Key InChIKey=OYCNDOVCOWSGBD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085004   

TargetAlpha-1A adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085004(1-(3-{[4-(4-Nitro-phenyl)-2,5-dioxo-1,2,5,7-tetrah...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]- prazosin from human recombinant Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085004(1-(3-{[4-(4-Nitro-phenyl)-2,5-dioxo-1,2,5,7-tetrah...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]- prazosin from human recombinant Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085004(1-(3-{[4-(4-Nitro-phenyl)-2,5-dioxo-1,2,5,7-tetrah...)
Affinity DataKi:  420nMAssay Description:Displacement of [3H]- prazosin from human recombinant Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed