BDBM50085137 6-Furan-2-yl-8-(3-nitro-phenyl)-[1,7]naphthyridine::CHEMBL162188

SMILES [O-][N+](=O)c1cccc(c1)-c1nc(cc2cccnc12)-c1ccco1

InChI Key InChIKey=PFKDOFDHKJKNBI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50085137   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085137(6-Furan-2-yl-8-(3-nitro-phenyl)-[1,7]naphthyridine...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085137(6-Furan-2-yl-8-(3-nitro-phenyl)-[1,7]naphthyridine...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibitory activity against Phosphodiesterase 4A (PDE4A) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085137(6-Furan-2-yl-8-(3-nitro-phenyl)-[1,7]naphthyridine...)
Affinity DataIC50:  510nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085137(6-Furan-2-yl-8-(3-nitro-phenyl)-[1,7]naphthyridine...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against Phosphodiesterase 4C (PDE4C) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed