BDBM50085145 CHEMBL161714::Trifluoro-methanesulfonic acid 8-(3-chloro-phenyl)-[1,7]naphthyridin-6-yl ester

SMILES FC(F)(F)S(=O)(=O)Oc1cc2cccnc2c(n1)-c1cccc(Cl)c1

InChI Key InChIKey=UPDYILNMMTZICX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50085145   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085145(CHEMBL161714 | Trifluoro-methanesulfonic acid 8-(3...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against Phosphodiesterase 4A (PDE4A) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085145(CHEMBL161714 | Trifluoro-methanesulfonic acid 8-(3...)
Affinity DataIC50:  48nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085145(CHEMBL161714 | Trifluoro-methanesulfonic acid 8-(3...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibitory activity against Phosphodiesterase 4C (PDE4C) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085145(CHEMBL161714 | Trifluoro-methanesulfonic acid 8-(3...)
Affinity DataIC50:  460nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed