BDBM50085353 CHEMBL293590::N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-ethyl-phenyl)-propionamide

SMILES CCc1ccc(CCC(=O)N[C@@H](Cc2ccccc2)C(=O)CCl)cc1

InChI Key InChIKey=DQQILLFRWAVJLK-IBGZPJMESA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50085353   

TargetChymotrypsin-like elastase family member 2A(Pig)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085353(CHEMBL293590 | N-((S)-1-Benzyl-3-chloro-2-oxo-prop...)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibitory activity against porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTrypsin(Pig)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085353(CHEMBL293590 | N-((S)-1-Benzyl-3-chloro-2-oxo-prop...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibitory activity against porcine pancreatic trypsin (TRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085353(CHEMBL293590 | N-((S)-1-Benzyl-3-chloro-2-oxo-prop...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibitory activity against human leukocyte cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymase(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085353(CHEMBL293590 | N-((S)-1-Benzyl-3-chloro-2-oxo-prop...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against human serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymotrypsinogen A(Bovine)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085353(CHEMBL293590 | N-((S)-1-Benzyl-3-chloro-2-oxo-prop...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibitory activity against alpha-chymotrypsin(alpha-CT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed