BDBM50085356 CHEMBL61933::N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(2-methoxy-phenyl)-propionamide

SMILES COc1ccccc1CCC(=O)N[C@@H](Cc1ccccc1)C(=O)CCl

InChI Key InChIKey=DYRDLGSOGTZXBW-KRWDZBQOSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50085356   

TargetCathepsin G(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085356(CHEMBL61933 | N-((S)-1-Benzyl-3-chloro-2-oxo-propy...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory activity against human leukocyte cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymotrypsinogen A(Bovine)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085356(CHEMBL61933 | N-((S)-1-Benzyl-3-chloro-2-oxo-propy...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibitory activity against alpha-chymotrypsin(alpha-CT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTrypsin(Pig)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085356(CHEMBL61933 | N-((S)-1-Benzyl-3-chloro-2-oxo-propy...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibitory activity against porcine pancreatic trypsin (TRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymotrypsin-like elastase family member 2A(Pig)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085356(CHEMBL61933 | N-((S)-1-Benzyl-3-chloro-2-oxo-propy...)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibitory activity against porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymase(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085356(CHEMBL61933 | N-((S)-1-Benzyl-3-chloro-2-oxo-propy...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory activity against human serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed