BDBM50085394 5-Pyridin-2-yl-thiophene-2-carboxylic acid [(E)-3-(5-carbamimidoyl-2-hydroxy-phenyl)-allyl]-amide::CHEMBL72350

SMILES NC(=N)c1ccc(O)c(\C=C\CNC(=O)c2ccc(s2)-c2ccccn2)c1

InChI Key InChIKey=ISQVFVSYFBMAFK-ONEGZZNKSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085394   

TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085394(5-Pyridin-2-yl-thiophene-2-carboxylic acid [(E)-3-...)
Affinity DataKi:  37nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085394(5-Pyridin-2-yl-thiophene-2-carboxylic acid [(E)-3-...)
Affinity DataKi:  1.40E+3nMAssay Description:In vitro inhibition of trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085394(5-Pyridin-2-yl-thiophene-2-carboxylic acid [(E)-3-...)
Affinity DataKi: >4.00E+3nMAssay Description:In vitro inhibition of coagulation factor IIa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed