BDBM50085783 CHEMBL438897::Gonadotropin Releasing Hormone analogue::dicyclo(1,1-5/4-10)[Ac-Glu(Gly)-DCpa-DTrp-Asp-Dbu-D2Nal-Leu-Arg-Pro-Dpr-NH2]

SMILES CC(=O)N[C@@H]1CCC(=O)NCC(=O)NCC[C@H]2NC(=O)[C@@H](CC(=O)NC[C@H](C(N)=O)NC(=O)[C@H]3CCCN3C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC2=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(Cl)cc2)NC1=O

InChI Key InChIKey=LHRIVOCEYCMNDZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085783   

TargetGonadotropin-releasing hormone receptor(Rat)
Salk Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085783BDBM50085783(dicyclo(1,1-5/4-10)[Ac-Glu(Gly)-DCpa-DTrp-Asp-Dbu-...)
Affinity DataKi:  0.240nMAssay Description:Affinity for rat gonadotrophin releasing hormone (GnRH) receptor using HEK293 cells transfected with rat Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085783BDBM50085783(dicyclo(1,1-5/4-10)[Ac-Glu(Gly)-DCpa-DTrp-Asp-Dbu-...)
Affinity DataKi:  0.240nMAssay Description:Binding affinity towards Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed