BDBM50085970 CHEMBL7318::[2-(5-Methoxy-2-phenyl-1H-indol-3-yl)-ethyl]-dimethyl-amine::[2-(5-Methoxy-2-phenyl-1H-indol-3-yl)-ethyl]-dimethyl-amine (C2H2O4)::[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethylamine, 5

SMILES COc1ccc2[nH]c(c(CCN(C)C)c2c1)-c1ccccc1

InChI Key InChIKey=VSGPGYWZVPDDSK-UHFFFAOYSA-N

Data  16 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50085970   

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  20nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]lysergic acid diethylamide from human 5-HT6 receptor transfected in HEK293 cells after 60 mins by liquid scintillation spectromet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  20nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  20nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  50nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  54nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptor expressed in HEK 293 human embryonic kidney cells, [3H]-lysergic acid diethylamide as radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  155nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  470nMAssay Description:Compound was evaluated for its binding affinity towards rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  675nMAssay Description:Compound was evaluated for its binding affinity towards rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  1.47E+3nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  4.70E+3nMAssay Description:Compound was evaluated for its binding affinity towards human serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  5.16E+3nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 5A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  6.23E+3nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 1E receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for its binding affinity towards human NET(norepinephrine) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed