BDBM50086038 6-chloro-2-methyl-1H,2'H,5'H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(::6-chloro-2-methylspiro[1,2,3,4-tetrahydroisoquinoline-4,3'-(tetrahydro-1'H-pyrrole)]-1,2',3,5'-tetraone::CHEMBL10382

SMILES CN1C(=O)c2ccc(Cl)cc2C2(CC(=O)NC2=O)C1=O

InChI Key InChIKey=NXVVCYVGZVGQBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086038   

TargetAldo-keto reductase family 1 member B1(Human)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50086038(6-chloro-2-methylspiro[1,2,3,4-tetrahydroisoquinol...)
Affinity DataIC50: 78.2nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed