BDBM50086061 5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (3-pyridin-2-yl-phenyl)-amide::CHEMBL14548

SMILES COc1cc2CCN(C(=O)Nc3cccc(c3)-c3ccccn3)c2cc1C(F)(F)F

InChI Key InChIKey=RHSKPMJDUUCLAL-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086061   

Target5-hydroxytryptamine receptor 2C(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086061(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine receptor 2C in HEK293 cells, using [3H]mesulergine as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086061(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Affinity DataKi:  501nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine receptor 2A in HEK293 cells, using [3H]ketanserin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086061(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of heterologously expressed human cytochrome P450 1A2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed