BDBM50087022 8-Indan-2-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL28172

SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C1Cc2ccccc2C1

InChI Key InChIKey=CQRVSNCDRSTFOM-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50087022   

TargetNociceptin receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087022(8-Indan-2-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  2.5nMAssay Description:Competitive binding affinity against transfected HEK293 cells expressing human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087022(8-Indan-2-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  26nMAssay Description:Competitive binding displacement analyses was performed from permanently transfected HEK293 cells expressing human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087022(8-Indan-2-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  161nMAssay Description:Competitive binding displacement analyses was performed from permanently transfected HEK293 cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087022(8-Indan-2-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataEC50:  500nMAssay Description:Effective concentration required to stimulate binding of GTPgammaS to Opioid receptor like 1 was determined using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087022(8-Indan-2-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  710nMAssay Description:Competitive binding displacement analyses was performed from permanently transfected HEK293 cells expressing human Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed