BDBM50087079 CHEMBL283201::N-[4-(3-Bromo-4-dimethylaminomethyl-phenylamino)-quinazolin-6-yl]-acrylamide

SMILES CN(C)Cc1ccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)cc1Br

InChI Key InChIKey=MWAIFRUFCZCDIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50087079   

TargetEpidermal growth factor receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087079(N-[4-(3-Bromo-4-dimethylaminomethyl-phenylamino)-q...)
Affinity DataIC50: 45nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087079(N-[4-(3-Bromo-4-dimethylaminomethyl-phenylamino)-q...)
Affinity DataIC50: 416nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed