BDBM50087636 (R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-3-(1-carbamimidoyl-piperidin-3-yl)-2-phenylmethanesulfonylamino-propionamide; TFA::CHEMBL162443

SMILES NC(=N)N1CCCC(C[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)NCC(=O)N[C@H]2CCCN(C2O)C(N)=N)C1

InChI Key InChIKey=CKRQXNYHHJWLPU-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50087636   

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087636((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)
Affinity DataIC50: 0.920nMAssay Description:In vitro inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087636((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)
Affinity DataIC50: 0.920nMAssay Description:In vitro inhibition of human Coagulation factor X.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087636((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)
Affinity DataIC50: 31nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087636((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)
Affinity DataIC50: 31nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087636((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)
Affinity DataIC50: 726nMAssay Description:In vitro inhibition of human plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087636((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)
Affinity DataIC50: 726nMAssay Description:In vitro inhibition of human plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087636((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087636((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed