BDBM50088004 8-hydroxy-11-[2-(2-methoxyphenyl)acetyl]-1-phenyl-(1R,8S,9S,13S)-11-azatetracyclo[6.5.2.02,7.09,13]pentadeca-2,4,6-triene-9-carboxylic acid (RPR114235)::CHEMBL52146

SMILES COc1ccccc1CC(=O)N1C[C@@H]2[C@@](C1)(C(O)=O)[C@]1(O)CC[C@@]2(c2ccccc2)c2ccccc12

InChI Key InChIKey=RJASOSFZMINXTC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088004   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50088004(8-hydroxy-11-[2-(2-methoxyphenyl)acetyl]-1-phenyl-...)
Affinity DataKi:  250nMAssay Description:Inhibition of farnesyltransferase by Ras/SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed