BDBM50088087 2-[(2,5-Dichloro-benzenesulfonyl)-(4-nitro-benzyl)-amino]-N-hydroxy-acetamide::CHEMBL301786

SMILES ONC(=O)CN(Cc1ccc(cc1)[N+]([O-])=O)S(=O)(=O)c1cc(Cl)ccc1Cl

InChI Key InChIKey=MZISFPSOTJFTTJ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50088087   

TargetInterstitial collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088087(2-[(2,5-Dichloro-benzenesulfonyl)-(4-nitro-benzyl)...)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088087(2-[(2,5-Dichloro-benzenesulfonyl)-(4-nitro-benzyl)...)
Affinity DataKi:  10nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088087(2-[(2,5-Dichloro-benzenesulfonyl)-(4-nitro-benzyl)...)
Affinity DataKi:  13nMAssay Description:Inhibitory activity against the Matrix Metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50088087(2-[(2,5-Dichloro-benzenesulfonyl)-(4-nitro-benzyl)...)
Affinity DataKi:  16nMAssay Description:Inhibitory activity against the Clostridium histolyticum collagenase (ChC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088087(2-[(2,5-Dichloro-benzenesulfonyl)-(4-nitro-benzyl)...)
Affinity DataKi:  17nMAssay Description:Inhibitory activity against the Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed