BDBM50088124 CHEMBL299091::N-Hydroxy-2-[(4-nitro-benzyl)-(2,4,6-trimethyl-benzenesulfonyl)-amino]-acetamide

SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=QFPRVWUEWDLNPU-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50088124   

LigandPNGBDBM50088124(N-Hydroxy-2-[(4-nitro-benzyl)-(2,4,6-trimethyl-ben...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against the Clostridium histolyticum collagenase (ChC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088124(N-Hydroxy-2-[(4-nitro-benzyl)-(2,4,6-trimethyl-ben...)
Affinity DataKi:  25nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088124(N-Hydroxy-2-[(4-nitro-benzyl)-(2,4,6-trimethyl-ben...)
Affinity DataKi:  29nMAssay Description:Inhibitory activity against the Matrix Metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088124(N-Hydroxy-2-[(4-nitro-benzyl)-(2,4,6-trimethyl-ben...)
Affinity DataKi:  36nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088124(N-Hydroxy-2-[(4-nitro-benzyl)-(2,4,6-trimethyl-ben...)
Affinity DataKi:  39nMAssay Description:Inhibitory activity against the Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed