BDBM50088129 CHEMBL54501::N-Hydroxy-2-[3-naphthalen-1-yl-1-(4-nitro-benzyl)-ureido]-acetamide

SMILES ONC(=O)CN(Cc1ccc(cc1)[N+]([O-])=O)C(=O)Nc1cccc2ccccc12

InChI Key InChIKey=HHSADBHNZPOTTJ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50088129   

LigandPNGBDBM50088129(N-Hydroxy-2-[3-naphthalen-1-yl-1-(4-nitro-benzyl)-...)
Affinity DataKi:  18nMAssay Description:Inhibitory activity against the Clostridium histolyticum collagenase (ChC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088129(N-Hydroxy-2-[3-naphthalen-1-yl-1-(4-nitro-benzyl)-...)
Affinity DataKi:  33nMAssay Description:Inhibitory activity against the Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088129(N-Hydroxy-2-[3-naphthalen-1-yl-1-(4-nitro-benzyl)-...)
Affinity DataKi:  35nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088129(N-Hydroxy-2-[3-naphthalen-1-yl-1-(4-nitro-benzyl)-...)
Affinity DataKi:  39nMAssay Description:Inhibitory activity against the Matrix Metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088129(N-Hydroxy-2-[3-naphthalen-1-yl-1-(4-nitro-benzyl)-...)
Affinity DataKi: >100nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed