BDBM50089182 (2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-2-carboxylic acid hydroxyamide::4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL279482

SMILES ONC(=O)[C@H]1C[C@H](C(=O)N1)c1ccc(Oc2ccc(F)cc2)cc1

InChI Key InChIKey=TUIHSDQRXNNCLL-LSDHHAIUSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50089182   

TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  82nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  82nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  39nMAssay Description:Inhibition of matrix metalloprotease -2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  1.56E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  1.56E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  39nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  700nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  703nMAssay Description:Inhibition of matrix metalloprotease -3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed