BDBM50089439 CHEMBL3578017

SMILES CC(=O)NC(CNC(=O)CCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1cccc2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)[C@@H](C)O

InChI Key InChIKey=NAITVKNZDVDBSV-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50089439   

TargetNeuropeptide Y receptor type 2(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089439BDBM50089439(CHEMBL3578017)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human neuropeptide Y Y2 receptor expressed in COS-7 cells cotransfected with chimeric Gi/q protein assessed as inositol phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089439BDBM50089439(CHEMBL3578017)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human neuropeptide Y Y2 receptor expressed in COS-7 cells cotransfected with chimeric Gi/q protein assessed as inositol phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089439BDBM50089439(CHEMBL3578017)
Affinity DataEC50:  40nMAssay Description:Inverse agonist activity at human GHSR1a receptor expressed in COS-7 cells assessed as inositol phosphate accumulation after 2 hrs by anion exchange ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089439BDBM50089439(CHEMBL3578017)
Affinity DataEC50:  42nMAssay Description:Inverse agonist activity at human GHSR1a receptor expressed in COS-7 cells assessed as inositol phosphate accumulation after 2 hrs by anion exchange ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089439BDBM50089439(CHEMBL3578017)
Affinity DataIC50: 61nMAssay Description:Displacement of [125I]PYY from human neuropeptide Y Y2 receptor expressed in HEK293 cells cotransfected with eYFP fusion protein after 2 hrs by compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089439BDBM50089439(CHEMBL3578017)
Affinity DataIC50: 63nMAssay Description:Displacement of [125I]PYY from human neuropeptide Y Y2 receptor expressed in HEK293 cells cotransfected with eYFP fusion protein after 2 hrs by compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089439BDBM50089439(CHEMBL3578017)
Affinity DataIC50: 97nMAssay Description:Displacement of [125I]ghrelin from human eYFP-fused ghrelin receptor expressed in COS7 cells after 75 mins by competitive receptor binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089439BDBM50089439(CHEMBL3578017)
Affinity DataIC50: 98nMAssay Description:Displacement of [125I]ghrelin from human eYFP-fused ghrelin receptor expressed in COS7 cells after 75 mins by competitive receptor binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed