BDBM50089490 4-{5-[(4-Fluoro-phenyl)-(3-methyl-ureido)-methyl]-[1,2,4]oxadiazol-3-yl}-N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-benzenesulfonamide::CHEMBL405245

SMILES CNC(=O)NC(c1nc(no1)-c1ccc(cc1)S(=O)(=O)Nc1ccc(CCNC[C@H](O)c2cccnc2)cc1)c1ccc(F)cc1

InChI Key InChIKey=DVYQAZHFWGJCRQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50089490   

TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50089490(4-{5-[(4-Fluoro-phenyl)-(3-methyl-ureido)-methyl]-...)
Affinity DataEC50:  3nMAssay Description:Stimulation of cAMP levels in CHO cells expressing the recombinant human beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50089490(4-{5-[(4-Fluoro-phenyl)-(3-methyl-ureido)-methyl]-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Binding affinity to recombinant human beta-2 adrenergic receptor prepared from CHO cells in the presence of [125I]iodocyanopindololMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50089490(4-{5-[(4-Fluoro-phenyl)-(3-methyl-ureido)-methyl]-...)
Affinity DataIC50: 4.50E+3nMAssay Description:Binding affinity to recombinant human beta-1 adrenergic receptor expressed in CHO cells in the presence of [125I]iodocyanopindololMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed