BDBM50089722 4-Benzo[1,3]dioxol-5-ylmethyl-5-(4-methoxy-benzyl)-2-(3-methoxy-benzyl)-2H-pyrazol-3-ol::CHEMBL3144728

SMILES COc1ccc(Cc2[nH]n(Cc3cccc(OC)c3)c(=O)c2Cc2ccc3OCOc3c2)cc1

InChI Key InChIKey=UPJNGEQMNVXCHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089722   

TargetEndothelin-1 receptor(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089722(4-Benzo[1,3]dioxol-5-ylmethyl-5-(4-methoxy-benzyl)...)
Affinity DataIC50: 7.50E+3nMAssay Description:In vitro inhibition of endothelin binding to endothelin A receptor in rat heart ventricles was measured using a 125-I labelled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089722(4-Benzo[1,3]dioxol-5-ylmethyl-5-(4-methoxy-benzyl)...)
Affinity DataIC50: 2.40E+4nMAssay Description:In vitro inhibition of [125-I] labelled ET-1 endothelin binding to Endothelin B receptor in rat cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed