BDBM50089723 4-Benzo[1,3]dioxol-5-ylmethyl-2-(2-methoxy-benzyl)-5-trifluoromethyl-2H-pyrazol-3-ol::CHEMBL3144729

SMILES COc1ccccc1Cn1[nH]c(c(Cc2ccc3OCOc3c2)c1=O)C(F)(F)F

InChI Key InChIKey=SNFRINHVKRZMNC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089723   

TargetEndothelin-1 receptor(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089723(4-Benzo[1,3]dioxol-5-ylmethyl-2-(2-methoxy-benzyl)...)
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of endothelin binding to endothelin A receptor in rat heart ventricles was measured using a 125-I labelled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089723(4-Benzo[1,3]dioxol-5-ylmethyl-2-(2-methoxy-benzyl)...)
Affinity DataIC50: 3.30E+4nMAssay Description:In vitro inhibition of [125-I] labelled ET-1 endothelin binding to Endothelin B receptor in rat cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed