BDBM50090002 CHEMBL411003::Dynorphin A (1-11)-NH2H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH2::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH2

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key InChIKey=OKJAOUBQLSWUNX-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090002   

TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090002BDBM50090002(Dynorphin A (1-11)-NH2H-Tyr-Gly-Gly-Phe-Leu-Arg-Ar...)
Affinity DataKi:  0.0740nMAssay Description:Binding affinity towards cloned human Opioid receptor kappa 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090002BDBM50090002(Dynorphin A (1-11)-NH2H-Tyr-Gly-Gly-Phe-Leu-Arg-Ar...)
Affinity DataEC50:  0.740nMAssay Description:Human kOpioid receptor kappa 1 mediated stimulation of [35S]- GTPgammaS binding in CHO cells (Agonist potency).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090002BDBM50090002(Dynorphin A (1-11)-NH2H-Tyr-Gly-Gly-Phe-Leu-Arg-Ar...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity towards cloned human Opioid receptor delta 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090002BDBM50090002(Dynorphin A (1-11)-NH2H-Tyr-Gly-Gly-Phe-Leu-Arg-Ar...)
Affinity DataKi:  7.60nMAssay Description:Binding affinity towards cloned human Opioid receptor mu 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed