BDBM50090271 2-[2-(4-Chloro-phenyl)-2-phenyl-acetylamino]-5-guanidino-pentanoic acid (S)-indan-1-ylamide::CHEMBL41686

SMILES NC(=N)NCCCC(NC(=O)C(c1ccccc1)c1ccc(Cl)cc1)C(=O)N[C@H]1CCc2ccccc12

InChI Key InChIKey=GUAYHTLGOSYHNP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090271   

TargetNeuropeptide Y receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090271(2-[2-(4-Chloro-phenyl)-2-phenyl-acetylamino]-5-gua...)
Affinity DataIC50: 3.00E+3nMAssay Description:NPY Y1-antagonistic activity in HEL cells by measuring the inhibition of porcine NPY (10 nM) stimulated increase in the intracellular [Ca2+] concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090271(2-[2-(4-Chloro-phenyl)-2-phenyl-acetylamino]-5-gua...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of binding of [3H]propionyl-NPY (1 nM) to Neuropeptide Y receptor type 1 in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090271(2-[2-(4-Chloro-phenyl)-2-phenyl-acetylamino]-5-gua...)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of binding of [3H]propionyl-NPY (1 nM) to Neuropeptide Y receptor type 5 in HEC-1-B cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090271(2-[2-(4-Chloro-phenyl)-2-phenyl-acetylamino]-5-gua...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of binding of [3H]propionyl-NPY (1 nM) to Neuropeptide Y receptor type 2 in SMS-KAN cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed