BDBM50090282 2-Biphenyl-4-yl-N-{1-(7-hydroxy-1,3,4,5-tetrahydro-benzo[c]azepine-2-carbonyl)-4-[N'-(3-phenyl-propyl)-guanidino]-butyl}-acetamide::CHEMBL290175

SMILES Oc1ccc2CN(CCCc2c1)C(=O)C(CCCNC(=N)NCCCc1ccccc1)NC(=O)Cc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=MDVBCKOUBZFSMR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090282   

TargetNeuropeptide Y receptor type 5(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090282(2-Biphenyl-4-yl-N-{1-(7-hydroxy-1,3,4,5-tetrahydro...)
Affinity DataIC50: 770nMAssay Description:Inhibition of binding of [3H]propionyl-NPY (1 nM) to Neuropeptide Y receptor type 5 in HEC-1-B cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090282(2-Biphenyl-4-yl-N-{1-(7-hydroxy-1,3,4,5-tetrahydro...)
Affinity DataIC50: 1.19E+4nMAssay Description:NPY Y1-antagonistic activity in HEL cells by measuring the inhibition of porcine NPY (10 nM) stimulated increase in the intracellular [Ca2+] concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090282(2-Biphenyl-4-yl-N-{1-(7-hydroxy-1,3,4,5-tetrahydro...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of binding of [3H]propionyl-NPY (1 nM) to Neuropeptide Y receptor type 1 in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090282(2-Biphenyl-4-yl-N-{1-(7-hydroxy-1,3,4,5-tetrahydro...)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of binding of [3H]propionyl-NPY (1 nM) to Neuropeptide Y receptor type 2 in SMS-KAN cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed