BDBM50090488 1-Benzyl-1,2,3,4-tetrahydro-isoquinoline-6,7-diol::CHEMBL298285

SMILES Oc1cc2CCNC(Cc3ccccc3)c2cc1O

InChI Key InChIKey=GGGSEBXTKMTNBW-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50090488   

TargetD(2) dopamine receptor(Rat)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50090488(1-Benzyl-1,2,3,4-tetrahydro-isoquinoline-6,7-diol ...)
Affinity DataKi:  640nMAssay Description:The compound has been evaluated for its binding affinity towards Dopamine receptor D2 by displacing the radioligand [3H]YM-09151-2 (0.5 nM) in rat st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50090488(1-Benzyl-1,2,3,4-tetrahydro-isoquinoline-6,7-diol ...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at beta2 adrenergic receptor in guinea pig tracheal smooth muscle assessed as inhibition of histamine-induced tracheal smooth muscle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50090488(1-Benzyl-1,2,3,4-tetrahydro-isoquinoline-6,7-diol ...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at beta2 adrenergic receptor in guinea pig tracheal smooth muscle assessed as inhibition of histamine-induced tracheal smooth muscle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhejiang Ocean University

Curated by ChEMBL
LigandPNGBDBM50090488(1-Benzyl-1,2,3,4-tetrahydro-isoquinoline-6,7-diol ...)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of recombinant full-length LSD1 (unknown origin) expressed in Escherichia coli BL21(DE) cells using H3K4me2 peptide as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50090488(1-Benzyl-1,2,3,4-tetrahydro-isoquinoline-6,7-diol ...)
Affinity DataKi:  9.27E+3nMAssay Description:The compound has been evaluated for its binding affinity towards Dopamine receptor D1 by displacing the radioligand [3H]SCH-23390 (1.5 nM) in rat str...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50090488(1-Benzyl-1,2,3,4-tetrahydro-isoquinoline-6,7-diol ...)
Affinity DataKi:  5.76E+4nMAssay Description:The compound has been evaluated for its binding affinity towards Dopamine transporter by displacing the radioligand [3H]GBR-12935 (1.0 nM) in rat str...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed