BDBM50090495 (R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-6-one O-(3-phenyl-propyl)-oxime::CHEMBL46536

SMILES Clc1ccc(cc1)[C@@H]1CCN2CC1\C(C2)=N\OCCCc1ccccc1

InChI Key

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090495   

TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090495((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  41nMAssay Description:Inhibition of [3H]DA binding to dopamine transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090495((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  53nMAssay Description:Inhibition of [3H]- Mazindol binding to dopamine transporter of rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090495((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  292nMAssay Description:Inhibition of [3H]-5-HT binding to serotonin transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090495((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  483nMAssay Description:Inhibition of [3H]NE binding to norepinephrine transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed