BDBM50090592 2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo-piperazin-1-yl]-N-[2-(3H-imidazol-4-yl)-ethyl]-acetamide::CHEMBL49510

SMILES O=C(CN1CCN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CC1=O)NCCc1cnc[nH]1

InChI Key InChIKey=XLJLQCXVEZVMCX-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50090592   

TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090592BDBM50090592(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  21nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090592BDBM50090592(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >2.90E+3nMAssay Description:Compound was evaluated for the inhibitory activity against trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090592BDBM50090592(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >4.00E+3nMAssay Description:Compound was evaluated for the inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090592BDBM50090592(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >7.30E+3nMAssay Description:Compound was evaluated for the inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090592BDBM50090592(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >8.70E+3nMAssay Description:Compound was evaluated for the inhibitory activity against t-PAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090592BDBM50090592(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >1.80E+4nMAssay Description:Compound was evaluated for the inhibitory activity against Activated protein CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed