BDBM50090623 3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-1-p-tolyl-1,5-dihydro-pyrrol-2-one::CHEMBL295068

SMILES Cc1ccc(cc1)N1CC(=C(C1=O)c1ccc(F)cc1)c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=LEZMCPKCMGTGPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090623   

TargetProstaglandin G/H synthase 2(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50090623(3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-1...)
Affinity DataIC50: 1.05E+3nMAssay Description:Biochemical index for Prostaglandin G/H synthase 2 measured as, PGE-2 levels in lipopolysaccharide (LPS)-challenged human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50090623(3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-1...)
Affinity DataIC50: 3.70E+3nMAssay Description:Biochemical index for Prostaglandin G/H synthase 1 measured as, thromboxane 2 (TXB2) levels following blood coagulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed