BDBM50090642 (2Z,6E)-7,11-dimethyl-3-(2-methylpropyl)dodeca-2,6,10-trien-1-yl (phosphonatooxy)phosphonate::3-substituted farnesyl diphosphate analogue

SMILES [#6]-[#6](-[#6])-[#6]\[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])=[#6]/[#6]-[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O

InChI Key InChIKey=RWAFXSQPFWYMNO-UHFFFAOYSA-K

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090642   

LigandPNGBDBM50090642((2Z,6E)-7,11-dimethyl-3-(2-methylpropyl)dodeca-2,6...)
Affinity DataIC50: 290nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed