BDBM50091556 CHEMBL3582316

SMILES Fc1ccc(nc1)-c1c[nH]c(n1)[C@H]1Cc2c([nH]c3ccccc23)C(N1)C1CCCCC1

InChI Key InChIKey=LRAQARBHUPYRAD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091556   

TargetSomatostatin receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091556(CHEMBL3582316)
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]SS-14 from human recombinant SSTR3 expressed in CHO cell membranes incubated for 60 to 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091556(CHEMBL3582316)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity against human recombinant SSTR3 expressed in CHO cells assessed as reduction in forskolin-induced cAMP accumulation in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091556(CHEMBL3582316)
Affinity DataIC50: 170nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed