BDBM50091647 5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1,3-dihydro-benzoimidazole-2-thione::CHEMBL116223

SMILES S=c1[nH]c2ccc(cc2[nH]1)C#CCN1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=SRVHJDODNPSAAA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091647   

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091647(5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1,3-di...)
Affinity DataIC50: 16nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091647(5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1,3-di...)
Affinity DataIC50: 2.50E+4nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2A NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091647(5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1,3-di...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2C NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed