BDBM50092700 4-[(1-Allyl-piperidin-4-ylidene)-phenyl-methyl]-N,N-diethyl-benzamide::CHEMBL126255

SMILES C=CCN1CCC(=C(c2ccccc2)c2ccc(C(=O)N(CC)CC)cc2)CC1

InChI Key InChIKey=KPCFAFSVHUASNQ-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50092700   

TargetDelta-type opioid receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092700BDBM50092700(4-[(1-Allyl-piperidin-4-ylidene)-phenyl-methyl]-N,...)
Affinity DataIC50: 3nMAssay Description:Binding affinity on cloned opioid receptor delta 1 in human HEK293S cells using [125I]-[D-Ala2]-deltorphin II as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092700BDBM50092700(4-[(1-Allyl-piperidin-4-ylidene)-phenyl-methyl]-N,...)
Affinity DataEC50:  28nMAssay Description:Effective concentration as delta agonist potency using [35S]GTP-gamma-S binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092700BDBM50092700(4-[(1-Allyl-piperidin-4-ylidene)-phenyl-methyl]-N,...)
Affinity DataIC50: 2.29E+3nMAssay Description:Binding affinity on cloned opioid receptor kappa 1 in human HEK293S cells using [125I]-D-Pro10-dynorphin A[1-11] as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092700BDBM50092700(4-[(1-Allyl-piperidin-4-ylidene)-phenyl-methyl]-N,...)
Affinity DataIC50: 3.33E+3nMAssay Description:Binding affinity on cloned opioid receptor mu 1 in human HEK293S cells using [125I]FK33824 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed