BDBM50092718 4-[(1-Butyl-piperidin-4-ylidene)-phenyl-methyl]-N,N-diethyl-benzamide::CHEMBL127802

SMILES [#6]-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccccc1)-c1ccc(cc1)-[#6](=O)-[#7](-[#6]-[#6])-[#6]-[#6]

InChI Key InChIKey=IOJRJGWYIUDOJN-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50092718   

TargetDelta-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092718(4-[(1-Butyl-piperidin-4-ylidene)-phenyl-methyl]-N,...)
Affinity DataIC50: 6.5nMAssay Description:Binding affinity on cloned opioid receptor delta 1 in human HEK293S cells using [125I]-[D-Ala2]-deltorphin II as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092718(4-[(1-Butyl-piperidin-4-ylidene)-phenyl-methyl]-N,...)
Affinity DataEC50:  46nMAssay Description:Effective concentration as delta agonist potency using [35S]GTP-gamma-S binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092718(4-[(1-Butyl-piperidin-4-ylidene)-phenyl-methyl]-N,...)
Affinity DataIC50: 4.13E+3nMAssay Description:Binding affinity on cloned opioid receptor mu 1 in human HEK293S cells using [125I]FK33824 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092718(4-[(1-Butyl-piperidin-4-ylidene)-phenyl-methyl]-N,...)
Affinity DataIC50: 4.27E+3nMAssay Description:Binding affinity on cloned opioid receptor kappa 1 in human HEK293S cells using [125I]-D-Pro10-dynorphin A[1-11] as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed