BDBM50093182 CHEMBL77007::Derivative of APC-2059

SMILES [#7]\[#6](-[#7])=[#7]/c1ccc(-[#6]-[#7]-[#6](=O)-[#7]-2-[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#8]-[#6]-[#6@H]-2-[#6]-3-[#6]-[#6]-[#6](-[#6]=[#6]-3)-[#6@@H]-2-[#6]-[#8]-[#6](=O)-[#7]-2-[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#7]-[#6]-c2ccc(cc2)\[#7]=[#6](/[#7])-[#7])cc1

InChI Key

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50093182   

TargetTryptase beta-2/delta/gamma(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093182(Derivative of APC-2059 | CHEMBL77007)
Affinity DataKi:  8nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093182(Derivative of APC-2059 | CHEMBL77007)
Affinity DataKi:  1.50E+4nMAssay Description:Compound was evaluated for its inhibitory potency against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093182(Derivative of APC-2059 | CHEMBL77007)
Affinity DataKi:  1.38E+5nMAssay Description:Compound was evaluated for its inhibitory potency against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093182(Derivative of APC-2059 | CHEMBL77007)
Affinity DataKi:  7.00E+5nMAssay Description:Compound was evaluated for its inhibitory potency against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed