BDBM50093325 1-(2-Amino-9H-purin-6-yloxy)-butan-2-one::CHEMBL337713

SMILES CCC(=O)COc1nc(N)nc2nc[nH]c12

InChI Key InChIKey=HKHVWPUUQMFZGF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50093325   

TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50093325(1-(2-Amino-9H-purin-6-yloxy)-butan-2-one | CHEMBL3...)
Affinity DataIC50: 9.32E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50093325(1-(2-Amino-9H-purin-6-yloxy)-butan-2-one | CHEMBL3...)
Affinity DataIC50: 9.45E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50093325(1-(2-Amino-9H-purin-6-yloxy)-butan-2-one | CHEMBL3...)
Affinity DataIC50: 1.51E+5nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed