BDBM50093797 Adamantane-1-carboxylic acid {1-[2-(4-cyano-phenyl)-ethyl]-pyrrolidin-3-yl}-amide::CHEMBL84240

SMILES N#Cc1ccc(CCN2CCC(NC(=O)C34CC5CC(CC(C5)C3)C4)C2)cc1

InChI Key InChIKey=CUOGJNWOVCPXJN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50093797   

TargetSerotonin 2 (5-HT2) receptor(Rat)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093797BDBM50093797(Adamantane-1-carboxylic acid {1-[2-(4-cyano-phenyl...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50093797BDBM50093797(Adamantane-1-carboxylic acid {1-[2-(4-cyano-phenyl...)
Affinity DataKi:  110nMAssay Description:Ability to displace [3H]-Prazosin binding to Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093797BDBM50093797(Adamantane-1-carboxylic acid {1-[2-(4-cyano-phenyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:The compound was evaluated for the ability to displace [3H]- 8-OH -DPAT from 5-hydroxytryptamine 1A receptor ( striata of male wistar rats)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed