BDBM50094261 CHEMBL3589968::US10544136, Compound 8

SMILES COc1ccc(cc1)-c1nc(no1)-c1ccccc1

InChI Key InChIKey=HHTORKBWIQPETA-PDYGGIGGSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50094261   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM50094261(CHEMBL3589968 | US10544136, Compound 8)
Affinity DataEC50:  7.30E+4nMAssay Description:The method involves contacting the receptor with a suitable concentration of an inventive compound to bring about activation of the receptor. The con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50094261(CHEMBL3589968 | US10544136, Compound 8)
Affinity DataIC50:  1.64E+4nMAssay Description:Antagonist activity at human full length FXR expressed in HeLa cells cotransfected with pSG5-human RXR after 24 hrs by Dual-Glo luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed