BDBM50094522 1,1,1-Trifluoro-3-[(3-fluoro-phenyl)-(2-trifluoromethyl-benzyl)-amino]-propan-2-ol::1,1,1-trifluoro-3-((3-fluorophenyl)(2-(trifluoromethyl)benzyl)amino)propan-2-ol::CHEMBL126972

SMILES OC(CN(Cc1ccccc1C(F)(F)F)c1cccc(F)c1)C(F)(F)F

InChI Key InChIKey=GRTUUSGOMZUDOM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50094522   

TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094522(1,1,1-Trifluoro-3-[(3-fluoro-phenyl)-(2-trifluorom...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human CETP-mediated transfer of [3H]CE from HDL to LDLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094522(1,1,1-Trifluoro-3-[(3-fluoro-phenyl)-(2-trifluorom...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Rabbit)
Al-Zaytoonah Private University of Jordan

Curated by ChEMBL
LigandPNGBDBM50094522(1,1,1-Trifluoro-3-[(3-fluoro-phenyl)-(2-trifluorom...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed