BDBM50094534 1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-isoindole::1,3-bis(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-isoindole::CHEMBL441663

SMILES Fc1ccc(cc1)-c1[nH]c(c2CCCCc12)-c1ccc(F)cc1

InChI Key InChIKey=PWORIKUKVBOCDD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50094534   

TargetProstaglandin G/H synthase 2(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094534(1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-is...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094534(1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-is...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094534(1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-is...)
Affinity DataIC50:  100nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed