BDBM50094697 1-[2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-(4-methoxy-phenyl)-urea::CHEMBL145734

SMILES COc1ccc(NC(=O)Nc2nc3nn(CCc4cccc5ccccc45)cc3c3nc(nn23)-c2ccco2)cc1

InChI Key InChIKey=VQYJAIHIXOQQPT-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50094697   

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094697(1-[2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyr...)
Affinity DataKi:  16nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094697(1-[2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyr...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells; range 14-19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094697(1-[2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyr...)
Affinity DataKi:  16nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094697(1-[2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyr...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A2b receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094697(1-[2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyr...)
Affinity DataKi:  2.47E+3nMAssay Description:Tested for inhibitory activity against human adenosine A1 receptor by displacement of [3H]-DPCPX expressed in CHO cells ; value ranges from 2362-2575More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094697(1-[2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyr...)
Affinity DataKi:  3.26E+3nMAssay Description:Displacement of [3H]-SCH- 58261 from human adenosine A2A receptor expressed in CHO cells; range 2826-3761More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094697(1-[2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyr...)
Affinity DataKi:  1.58E+4nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed